Viewing Cancer As A Physics Problem Suggests New Treatments
For nearly 40 years, I have been working on fighting cancer from an unusual angle. Trained initially as an engineer, I see tumors in part as a physics challenge and ask: How do their structural features promote their growth and keep cancer-fighting drugs from working effectively? More than two decades ago, for instance, my co-workers and I, then at Carnegie Mellon University, revealed that structural abnormalities in tumor blood vessels interfere with drug delivery to malignant cells in a mass....